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To determine if acute stress activates pancreatic noradrenergic nerves, pancreatic norepinephrine (NE) output (spillover) was measured in halothane-anesthetized dogs. Central neuroglucopenia, induced by intravenous 2-deoxy-D-glucose (12-DGJ 600 mg/kg + 13.5 mg/kg-' per min') increased pancreatic NE output from a baseline of 380±100 to 1,490±340 pg/min (A = +1,110±290 pg/min, P < 0.01). Surgical...
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ژورنال
عنوان ژورنال: Nature Reviews Neuroscience
سال: 2001
ISSN: 1471-003X,1471-0048
DOI: 10.1038/35097522